潮气呼吸肺功能动态监测在毛细支气管炎治疗中的作用

摘要

目的 分析潮气呼吸肺功能动态监测在毛细支气管炎治疗中的作用.方法 对60例毛细支气管炎患儿分别于感染急性期、治疗后1周及恢复期1个月行潮气呼吸肺功能测定,主要测定参数为达峰时间比(TPTEF/TE)、达峰容积比(VPTEF/VE)、峰流速(PEF),比较各期肺功能指标及潮气流速容量环(TBFV环)变化.结果 毛细支气管炎患儿感染急性期小气道指标TPTEF/TE、VPTEF/VE明显低于治疗后1周及恢复期1个月,大气道指标PEF高于治疗后1周及恢复期1个月;各期比较,急性期与治疗后1个月比较有显著性差异(P均<0 05),TBFV环渐趋饱满.结论 毛细支气管炎患儿急性期为克服以小气道为主的气道阻塞,存在用力呼气,经治疗1周后各项指标明显好转,但仍低于恢复期,表明毛细支气管炎患儿急性期过后仍应坚持非特异性抗炎治疗;TPTEF/TE、VPTEF/VE等潮气呼吸肺功能测定可较好反映病情,评价喘息患儿气道阻塞变化.%Objective IL is Lo analyze Lhe eiiecL oi' lung function LesL via Lidal breaLhing in Lhe LreaLmenL lor bronchioliLis. Methods 60 children wiLh bronchioliLis were measured wiLh Lidal How volume curve 1'uncLion LesL in acuLe phase, Lhen Lhe LesL was repeaLed aiLer 1 week and 1 monLh laLer. The main parameLers were: Lime Lo peak raLio( TPTEF/TE ) , peak volume raLio ( VPTEF/VE ) , peak expiraLory How ( PEF ), comparing Lhe changes oi lung iuncLion and Lidal breaLhing How volume. Results In acuLe period, Lhe index of TPTEF/TE , VPTEF/VE were significanLly lower buL Lhe index of PEF were higher Lhan LhaL in 1 week and 1 monLh laLer. There were signiiicanL differences in Lhe indexes beLween acuLe phase and 1 monLh, and TBFV loop was becoming lull. Conclusion The children wiLh bronchioliLis have alLeraLion oi airway obsLrucLion, mainly in small airway, Lhe indicators are improved markedly in 1 week ai'Ler LreaLmenL, buL sLill lower Lhan Lhe recovery of 1 monLh. IL shows LhaL ai'Ler Lhe acuLe phase oi'bronchioliLis, Lhe paLienLs should adhere Lo non-specific anLi-inflammaLory LreaLmenL. TPTEF/TE, VPTEF/ VE and oLher Lidal breaLhing lung iuncLionmay may have a beLLer response Lo Lhe disease and evaluation ior Lhe changes in airway obsLrucLion in children wiLh wheezing.