首页> 中文期刊> 《现代中西医结合杂志》 >硫酸镁微量气泵吸入治疗毛细支气管炎的疗效及对实验室指标的影响

硫酸镁微量气泵吸入治疗毛细支气管炎的疗效及对实验室指标的影响

             

摘要

Objetci ve It is to investigate the curative effect of Magnesium sulfate micro air pump suction on bronchiolitis and the effect on the relevant experimental indexes , thus to seek the best medication way for clinical treatment .Methods 94 cases of children with bronchiolitis were randomly divided into 2 groups:both the groups were treated with normal therapy ,on the basis of this treatment , the observation group of 47 cases were given 25% MgSO4 solution by inhalation , 47 cases of the control group were given normal saline by the same amount of inhalation therapy , the changes of clinical scores , laboratory in-dexes and signs of the patients in both groups were observed before and after treatment .Results After 24 h treatment , arterial oxygen saturation , arterial partial pressure of carbon dioxide , arterial partial pressure of oxygen were improved compared with those before treatment(P<0.05), no significant difference in the indexes above was found before and after treatment in con -trol group(P>0.05), the improvement of the indexes above in the observation group was better than those in the control group (P<0.05).The clinical scores, signs, hospitalization time in the observation group was better while the effective rate was higher than those in the control group (P<0.05).Conclusion Magnesium sulfate micro air pump inhalation in the treatment of bronchiolitis can effectively improve the hypoxia wheeze , shorten the course of disease , promote the recovery of pulmonary function ,it can be used as the main route of administration in clinic and is worthy of reference .%目的:探讨硫酸镁微量气泵吸入治疗毛细支气管炎的疗效及对相关实验指标的影响,为临床治疗寻求最佳的用药途径。方法将94例毛细支气管炎患儿随机分为2组,2组均予常规治疗,观察组47例在此基础上应用25%硫酸镁溶液吸入治疗,对照组47例给予等量的生理盐水进行吸入治疗。观察2组患儿治疗前后临床评分、各实验室指标及体征变化。结果经24 h治疗后,观察组的动脉血氧饱和度、动脉血二氧化碳分压、动脉血氧分压均较治疗前有所改善(P均<0.05),对照组治疗前后上述指标无明显改善(P均>0.05),观察组上述指标改善情况优于对照组(P均<0.05)。观察组临床评分、体征、住院时间等明显优于对照组(P均<0.05),有效率明显高于对照组(P<0.05)。结论硫酸镁微量气泵吸入治疗毛细支气管炎,可有效改善患儿缺氧憋喘,缩短病程,促进肺功能恢复,在临床上可作为常用的给药途径,值得借鉴推广。

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