Objective To analyze the macroscopic tonsillectomy combined with endoscopic retro-grade bilious stone (LC+ERCP) treatment of gallstones and secondary clinical efficacy of common bile duct stones. Methods January 2012~2014 January our hospital for treatment of gallstones and bilious stones in 108 patients, using a random number table method of 108 patients were di-vided into two groups and the control group, 54 cases. Administered to the control group of pa-tients with conventional open surgery treatment, patients were observed LC+ERCP treatment. Com-pared two groups of patients with operative time, blood loss,postoperative discharge time, defeca-tion time, postoperative fasting time, hospital stay and hospital costs. Contrast the situation and the relapse rate in patients with postoperative complications in the two groups. Results The pa-tient's operation time, blood loss,postoperative discharge time, defecation time, postoperative fasting time, hospital stay and hospital costs were significantly less than the control group of patients, comparing the difference between the two groups statistically significant (P<0.05). The incidence of postoperative complications and relapse rate of patients in the observation group was significantly lower than the control group were compared between the two groups was statistically significant (P<0.05). Conclusion LC+ERCP treatment of gallstones and secondary bile duct stones than con-ventional open surgery has better clinical efficacy, and the incidence of postoperative complica-tions and recurrence rate is low, it is possible tofurther promote and clinical use.%选取2012年1月～2014年1月我院收治的108例胆囊结石合并胆总管结石患者，随机分为观察组和对照组各54例。对照组给予患者常规开腹术治疗，观察组患者LC+ERCP术治疗。对比两组患者的手术时间、术中出血量、术后排气时间、术后排便时间、术后禁食时间、住院天数和住院费用。对比两组患者术后并发症发生情况和复发率。结果观察组患者的手术时间、术中出血量、术后排气时间、术后排便时间、术后禁食时间、住院天数和住院费用均显著少于对照组，比较两组间差异具有统计学意义（P＜0.05）。观察组患者的术后并发症发生率和复发率均显著低于对照组，比较两组间差异具有统计学意义（P＜0.05）。LC+ERCP治疗胆囊结石并继发胆总管结石较常规开腹手术具有较好的临床疗效，且术后并发症发生率和复发率也较低，可以在临床进一步推广和使用。
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