胃肠癌化疗患者PICC置管时机与发生静脉炎的相关性分析

摘要

目的 分析胃肠癌化疗患者经外周静脉置入中心静脉导管(peripherally inserted central catheters,PICC)的置管时机与静脉炎的相关性.方法 选择2008年1月～2011年2月在本科室住院的胃肠癌术前应用PICC行化疗的患者153例,根据置管时机分为化疗前置管组(Ⅰ组),化疗中置管组(Ⅱ组),化疗间歇期置管组(Ⅲ组),比较3组患者静脉炎的发生率及其严重程度.结果 Ⅰ组患者静脉炎发生率最低,静脉炎的程度最轻(均P＜ 0.05).结论 胃肠癌患者首次化疗前应用PICC有利于降低静脉炎发生率,发生静脉炎的程度较轻,是PICC置管的最佳时机.%Objective To explore the relationship between the right time for catheterization of peripheral inserted central catheters (PICC) and phlebitis in the gastrointestinal cancer patients during chemotherapy. Methods 153 patients undergoing chemotherapy by PICC before gastrointestinal surgery in our department from January 2008 to February 2011 were assigned into pre-chemotherapy, infra-chemotherapy and intermission groups. The three groups were compared in respect of incidence rate and severity of phlebitis. Result The incidence in the pre-chemotherapy group was the lowest and the severity of phlebitis was the slightest (P < 0.05). Conclusions PICC catheteration at first chemotherapy for the gastrointestinal cancer patients before gastrointestinal surgery may be effective for lowering the incidence of phlebitis and reduce its severity as well. So pre-chemotherapy catheteration of PICC may be best.