新癀片调醋外敷预防多柔吡星所致静脉炎的效果观察

摘要

Objective To probe into the preventive effect of Xinhuang tablet dissolved in vinegar on phlebitis caused by Doxorubicin� Methods The self-control study was performed in 30 patients treated by doxorubicin� In the initial course,33%magnesium sulfate by wet dressings was externally applied on the skin along the vein until completion of transfusion of chemotherapeutic drugs� In the second course,Xinhuang tablet dissolved in vinegar was used on the skin along the vein until completion of transfusion�The phlebitis rate by magnesium sulfate by wet dressings was compared to that by Xinhuang tablet dissolved in vinegar� Result The phlebitis rate in the initial course was 83�3% while 36�7% in the second course(P<0�01)� Conclusions Xinhuang tablet dissolved in vinegar applied on the skin may be of use for the prevention of phlebitis� It may reduce the damage and improve the quality of the life�%　　目的探讨新癀片调醋预防多柔吡星所致静脉炎的效果。方法采用自身对照法，对30例应用多柔吡星化疗的患者，于第1疗程在前臂静脉留置套管针输注化疗药物时，沿静脉走向在皮肤表面外敷33%硫酸镁纱布至化疗药物输注完毕；于第2疗程在对侧前臂静脉留置套管针输注化疗药物时，沿静脉走向在皮肤表面外敷新癀片（研末）调醋至化疗药物输注完毕。观察两个疗程化疗后患者静脉炎发生率情况。结果第1疗程静脉炎发生率为83�3%，第2疗程静脉炎发生率为36�7%，两个疗程比较，P ＜0�01，差异具有统计学意义。结论新癀片调醋外敷能有效预防多柔吡星所致静脉炎，减轻静脉炎损伤程度，从而提高患者生活质量。