119例导尿管相关性尿路感染的病原体分布及耐药性分析

摘要

Objective To obtain the pathogens distribution and drug resistance characteristics of catheter associated urinary tract infection (CAUTI), so as to provide the evidence of controlling urinary tract infection .Methods 119 cases of CAUTI microbial culture and drug sensitive were collected and analyzed from January 2012 to June 2014.Results Isolated 97 pathogens from 119 urine specimens.Top 6 pathogens were:Escherichia coli (26.80%), Enterococcus faecalis (15.46%), Candida albicans (11.34%), Feces Enterococcus (10.31%), Pseudomonas aeruginosa (5.15%), Coagulase negative staphylococcus (5.15%), and the multi-drug-resistance was found.Some bacterial resistance rate was higher than the results of chinet 2013 surveillance.Conclusion The surveillance of bacterial resistance and the supervision of clinical rational drug use should be enhanced , and the further heavy interven-tions should be necessary to prevent the contact transmission of the multidrug -resistant organisms and CAUTI also .%目的：掌握导尿管相关性尿路感染（ catheter associated urinary tract infection ，CAUTI）的病原体分布以及耐药性特征，为控制尿路感染提供依据。方法通过统计2012年1月－2014年6月解放军81医院119例CAUTI尿液微生物培养及药敏结果，分析CAUTI病原体分布及耐药性特征。结果119例CAUTI尿液标本中检出病原菌97株，前6位病原体依次为大肠埃希菌（26．80％）、粪肠球菌（15．46％）、白色念珠菌（11．34％）、屎肠球菌（10．31％）、铜绿假单胞菌（5．15％）和凝固酶阴性葡萄球菌（5．15％），并呈现出多耐药性，部分耐药率超过2013年Chinet的相关监测结果。结论应加强CAUTI病原体耐药性监测和临床合理用药监管，重视对多重耐药菌的隔离预防和对CAUTI的预防干预。