134例痰结核分枝杆菌药敏结果分析

摘要

Objective To collect the data of drug resistance to evaluate the prevalence trend of 13 antituberculosis drugs and 3 combined drugs, so as to provide basic data for tuberculosis( TB )prevention and treatment. Methods Drug susceptible tests were done in 134 strains of Bacillus tuberculosis isolated from sputum specimens in clinic patients. Results The general drug resistance rate was 48.65％ , and multi-drug resistance rate was 54.48％. Conclusion The drug resistance and multi-drug resistance of pulmonary tuberculosis are still serious and effective, control of drug resistant tuberculosis is critical task currently.%目的 了解河南省胸科医院住院患者痰标本分离结核分枝杆菌对13种单一药物和3种联合药物的耐药情况,为临床指导用药提供依据.方法 对134例患者痰培养出的结核分枝杆菌采用绝对浓度间接法,进行13种单一抗结核药物和3种复合药物药敏试验.结果 总体耐药率为48.65%,耐多药结核病发生率为54.48%.结论 耐药和耐多药肺结核病疫情严重,有效控制耐药结核病是当前所面临的紧迫任务.