咪唑斯汀在皮肤科的应用现状及新进展

摘要

咪唑斯汀是第二代新型抗组胺药物,对H1受体具有较强的选择性和特异性,其抗组胺作用不仅起效快,而且持续时间长,药效能维持24 h,且无抗胆碱、抗肾上腺素及抗5-羟色胺活性.如今,咪唑斯汀被广泛应用于皮肤科各种疾病的治疗中,如急性及慢性荨麻疹、湿疹、各种皮炎等.现就近年来此药在皮肤科临床应用中的进展予以综述.%Mizolastin is the second generation of antihistamine, with strong selectivity and specificity to histamine H1 -receptor,which has no anticholinergic,resistance to adrenaline and resistance to 5-HT activity. Mizolastin has a quick and long antihistamine effect( up to 24 h ), and has been widely used in dermatological treatment,such as acute and chronic urticaria,eczema,and various dermatotes. Here is to make a review on the clinical application of mizolastin in dermatology in recent years.