Objective To discuss the curative effect of functional exercise assisted acupuncture and massage in treatment of osteoporotic spine degeneration combined with diabetes mellitus. Methods A total of 174 cases with osteoporotic spine degeneration combined with diabetes mellitus admitted to Guanganmen Hospital,Chinese Academy of Traditional Chinese Medicine from Sep. 2012 to Sep. 2013 were included and divided into two groups according to random-number table method. Observation group of 110 cases were treated with functional exercise assisted acupuncture and massage therapy. Control group of 64 cases were treated with acupuncture and massage therapy only. Continuous exercise of 15 days as a course of treatment,and two courses were administered continu-ously. The curative effect,analgesic effect,inflammation factors level,adverse reactions and the treatment compli-ance rate between the two groups were compared. Results Total effective rate of the observation group was signifi-cantly higher than the control group[96. 4%(106/110) vs 84. 4%(54/64),P<0. 05]. After treatment,visual ana-log scale of the observation group was lower than the control group[(2.23 ±0.23) point vs (3.15 ±0.26) point], onsettimeoftheobservatongroupwasshorterthanthecontrolgroup[(0.31±0.04) t/hvs(0.70±0.13) t/h], maintenance time of the observation group was longer than the control group[(33 ±5) t/h vs (19 ±5) t/h],the differences were statistically significant (P<0. 01). After treatment,the levels of tumor necrosis factorαand inter-leukin 1β of the observation group were significantly lower than those in the control group[(1. 11 ± 0. 25) mg/L vs (1.50 ±0.34) mg/L;(0.21 ±0.06) mg/L vs (0.33 ±0.05) mg/L],the differences were statistically signif-icant(P<0. 01). There was no significant difference in the incidence of adverse reactions between the two groups (P>0. 05). The treatment compliance rate of the observation group was 98. 2% (108/110),higher than that of the control group′s 87. 5%(56/64),the difference was statistically significant(P<0. 05). Conclusion Func-tional exercise assisted acupuncture and massage for the treatment of osteoporotic spine degeneration combined with diabetes mellitus,can alleviate the patients′pain,improve the mobility function,reduce inflammatory factor level, promote the clinical curative effect and treatment compliance,thus is of promotion value.%目的：探讨功能锻炼辅助针灸推拿治疗骨质疏松性腰椎退变合并糖尿病的疗效。方法选择2012年9月至2013年9月中国中医科学院广安门医院收治的174例骨质疏松性腰椎退变合并糖尿病患者为研究对象，采用随机数字表法分为两组：观察组110例，采用功能锻炼辅助针灸推拿疗法进行治疗，连续锻炼15 d为1个疗程；对照组64例仅采用针灸推拿治疗。连续治疗2个疗程。比较两组患者的临床疗效、镇痛效果、炎性因子水平、不良反应发生情况及治疗依从率。结果观察组总有效率显著高于对照组[96．4%(106/110)比84．4%(54/64)]，差异有统计学意义(P<0．05)。治疗后观察组视觉模拟评分低于对照组[(2．23±0．23)分比(3．15±0．26)分]，起效时间短于对照组[(0．31±0．04) t/h比(0．70±0．13) t/h]，维持时间长于对照组[(33±5) t/h比(19±5) t/h]，差异均有统计学意义(P<0．01)。治疗后，观察组肿瘤坏死因子α和白细胞介素1β水平均显著低于对照组[(1．11±0．25) mg/L 比(1．50±0．34) mg/L；(0．21±0．06) mg/L比(0．33±0．05) mg/L]，差异均有统计学意义(P<0．01)。两组不良反应发生率比较差异无统计学意义( P >0．05)。观察组治疗依从率为98．2%(108/110)，高于对照组87．5%(56/64)，差异有统计学意义(P<0．05)。结论功能锻炼辅助针灸推拿用于骨质疏松性腰椎退变合并糖尿病的治疗，能缓解患者疼痛，改善其活动功能，降低炎性因子水平，进而提升临床疗效和治疗依从性，具有推广价值。
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