干扰素在中枢神经系统感染疾病中的应用研究进展

摘要

Central nervous system( CNS) infection is a fatal disease that often occurs in young children . Substantial survivors develop neurological sequelae, ranging from learning and behavioral disorders to sei-zures.How to optimize the treatment of CNS infections has always been an issue of great concern .Interferon as a kind of protective cytokine,because of its characteristics such as antiviral and the regulation of immune balance and cell proliferation ,has drawn attention from more and more researchers at home and abroad .Better results were obtained in the treatment by interferon ,especially in immunocompromised patients .%中枢神经系统感染是一种严重威胁患儿生命的感染性疾病，发生智力低下、癫痫等各种后遗症的概率较高，如何优化中枢神经系统感染疾病的治疗一直是大家关心的热点。干扰素作为一类保护性的细胞活性因子，以其抗病毒、抗细胞增殖、调节免疫功能等特性，使许多常规药物治疗无效的疾病或体质弱、免疫功能低下的患者在治疗后收到良好的效果，越来越多的国内外研究者致力于对其的研发和应用。