扩散张量及扩散峰度成像技术在慢性酒精中毒性脑病中的应用

摘要

Alcohol is an addictive substance that is likely to cause chronic alcoholism encephalopathy ( CAE) .CAE dis-ease affects the quality of life of patients in varying degrees ,so early detection and diagnosis of the disease is particularly important for the clinical decision making .The use of imaging techniques , especially magnetic resonance imaging techno-logy,not only can directly reflect the signal changes in the brain parenchyma ,but also realize quantitative analysis by meas-uring the specific parameters of the changes in brain parenchyma .At present , the commonly used inspection methods at home and abroad are mainly magnetic resonance imaging .The main imaging techniques include diffusion tensor imaging and diffusion kurtosis imaging .%酒精是一种成瘾性物质,长期嗜酒容易导致慢性酒精中毒性脑病(CAE).CAE不同程度地影响患者的生活质量,因此早期发现并确诊该病对于临床决策尤为重要.利用影像学技术特别是磁共振成像技术不仅可以直观反映该病在脑实质中的信号变化,还可以通过测量具体的参数对脑实质的变化情况进行定量分析.目前国内外常用的检查手段主要是磁共振功能成像,其主要成像技术包括扩散张量成像及扩散峰度成像.