红细胞分布宽度与血栓性疾病的研究进展

摘要

Red cell distribution width ( RDW) is an indicator of erythrocyte variability in the blood circulation ,and can reflect the difference in red blood cell size and the dispersion degree of red blood cell volume .The study found that RDW is related to the incidence and prognosis of thrombotic diseases such as acute coronary syndrome , cerebral apoplexy , deep venous thrombosis,and so on.It is a strong predictor of thrombotic diseases .At present, the mechanism of interaction between RDW and thrombotic disease is not clear ,which may be related to malnutrition ,neuroendocrine ,inflammation and so on.Although RDW is not a specific index,the acquisition of RDW is simple and convenient ,with low cost,high repeat-ability,and it indirectly reflects the condition of patients with thrombotic disease ,so it is worthy of attention and promotion in clinical.%红细胞分布宽度(RDW)是测量血液循环中红细胞大小变异性的一个指标,同时也可反映红细胞大小差异性以及红细胞体积的离散程度.研究发现RDW与急性冠状动脉综合征、脑卒中、深静脉血栓形成等血栓性疾病的发生、病死率、预后存在相关性,是血栓性疾病的强预测指标.目前,RDW与血栓性疾病间的作用机制尚未明确,可能与营养不良、神经内分泌、炎症反应等有关.虽然RDW不是特异性指标,但RDW的获取简单便捷、费用低、可重复性强,且间接反映血栓性疾病患者的病情,值得临床重视和推广.