Objective The present study was performed to clarify the impact of endothelial function and clinical effect in cardiac syndrome-X after using Danhong injection. Methods 90 patients with cardiac syndrome- X were randomly divided into low-dosage Danhong injection (group A) and high-dosage Danhong injection (group B) and Danshen injection control group (group C). Every group was treated for 14 d. The symptom remittence. Treadmill test improvement and endothelial function were observed. Results The level of NO and flow-mediated dilatation in A and B group was significantly higher than that in group C. Symptoms in group A and group B were alleviated and treadmill test were improved than that in C group. Conclusion Danhong injection can obviously improve symptom of and ST-T changes of ECG.%目的 观察丹红注射液对X综合征(CSX)病人内皮功能变化、临床疗效及平板运动试验的影响.方法 对 90例42～72岁X综合征病人.在常规西药的基础上随机分为3组,分别为丹红注射液高剂量组(A组)、(Ⅱ)常规剂量组(B组)和丹参注射液组(C组),静点两周后比较三组中血管内皮功能变化,临床症状和平板运动试验后ST-T改变.结果 A组和B组在升高一氧化氮(NO)水平、血流介导的血管扩张(FMD)均明显高于C组；在症状缓解、平板试验改善方面AB组强于C组.结论 丹红注射液能改善血管内皮功能,改善心绞痛症状及平板试验心电图ST-T变化.
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