Objective To estimate the effective of capsules Kouyanqing to treat OLP. Methods Patients were divided into controlled and experiment groups. The controlled group were treated with Hypoglaucum and vitamin B as well as oral ulcer oil if necessary,while the experiment group were treated with Capsules Kouyanqing and vitamin B as well as oral ulcer oil if necessary. The short-term (4 weeks) and long-term (6 months) effects were observed. Results ShortteRm (4 weeks)and long-term (6 months) effects of experiment group were significantly better than that of the controlled group. Conclusion The capsules Kouyanqing combined with vitamin B adjust the immunity of human body, repair the damaged oral mucosa, thus reduce the recurring.%目的 观察中成药口炎清胶囊治疗口腔扁平苔藓(Oral Lichen Planus,OLP)的疗效.方法 对我院196例OLP患者随机分为治疗组及对照组.对照组采用昆明山海棠加复合维生素B,辅助口腔溃疡油进行治疗;治疗组采用我院自发研制的中成药口炎清胶囊加复合维生素B,辅助口腔溃疡油进行治疗.比较两组的近期(4周)和远期(6个月)疗效.结果 治疗组的近期和远期有效率均显著高于对照组,差异有统计学意义(P<0.05).结论 采用中成药口炎清胶囊治疗OLP能发挥各君臣药的互补作用,而复合维生素B含有多种辅酶,能参与体内多种营养物质代谢反应.该治疗方法通过调节机体的免疫机制,有利于口腔黏膜细胞的修复,巩固疗效,减少复发,疗效满意.
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