目的 探讨乳腺癌改良根治术中保留助间臂神经的临床疗效.方法 随机将60例乳腺癌患者,分为对照组(乳腺癌改良根治术时不保留肋间臂神经)和观察组(乳腺癌改良根治术时保留肋间臂神经),每组各30例,对两组术后并发症,以及术后患侧腋窝、上臂内侧皮肤感觉功能异常局部复发情况等指标,进行观察和比较.结果 观察组术后并发症发生率(10.0%)与对照组(13.3%)相比,没有明显改变(P>0.05);观察组术后患侧腋窝、上臂内侧皮肤感觉功能异常情况发生率(10.0%)与对照组相比(60.0%),有明显降低(P<0.05);平均随访3年,两组患者均没有出现局部复发以及远处转移等情况.结论 乳腺癌改良根治术中保留肋间臂神经能够明显降低患者术后的皮肤感觉功能异常情况,提高患者的预后质量,局部复发率低,值得临床推广应用.%Objective To study the efficacy observation and clinical analysis of intercostobrachial nerve reservation in the modified radical mastectomy. Methods 60 patients with breast cancer were randomized into the control group (without reservation the intercostobrachial nerve during the modified radical mastectomy) and the observation group (reservation the intercostobrachial nerve during the modified radical mastectomy), 30 patients per group. The postoperative complications, and postoperative skin and sensory function abnormality in axillary and medial upper arm, and the local recurrence during 3-year-follow-up period were observed and compared. Results Compared with the control group (10.0%), the postoperative complications in the observation group was not obviously changed (13.3%), P>0. 05. Compared with the control group (60. 0%), the incidence of postoperative skin and sensory function abnormality in axillary and medial upper arm in the observation group was significantly decreased (10, 0%) , P<0. 05; With 3-year-follow-up period, no patient with local recurrence and distant metastasis was observed in the two groups. Conclusion The reservation the intercostobrachial nerve during the modified radical mastectomy was able to obviously decrease the postoperative skin and sensory function abnormality, improve the quality of the prognosis with the low local recurrence rate, and worthy of clinical promotion.
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