目的:探究高压氧治疗脑外伤的疗效及对外周血CD+34的影响.方法:选取2017年6月1日-2018年6月1日在本院诊断及治疗的脑外伤患者80例, 采用随机数表法分为观察组与对照组, 每组各40例, 对照组采用常规脑外伤及支持治疗, 观察组在对照组的基础上予以高压氧治疗.对比两组治疗疗效及GOS分级, 治疗前后GCS、DRS及外周血CD34+水平.结果:观察组治疗总有效率82.50%显著高于对照组60.00%, 两组比较差异有统计学意义 (字2=4.942, P=0.026) .治疗后观察组GCS评分显著高于对照组 (t=5.221, P=0.000), 且GOS分级>Ⅳ级例数显著高于对照组 (字2=14.459, P=0.000) .治疗后观察组DRS评分显著低于对照组 (t=2.822, P=0.000) .治疗后第3~11天观察组CD34+水平显著高于治疗前 (P<0.05), 且高于同时期对照组 (P<0.05) .结论:高压氧治疗脑外伤疗效肯定, 且能有效提高外周血CD34+水平.%Objective:To explore the effect of hyperbaric oxygen on brain injury and CD34+ in peripheral blood.Method:From June 1, 2017 to June 1, 2018, 80 cases of cerebral trauma patients diagnosed and treated in our hospital were randomly divide into observation group (40 cases) and control group (40 cases).The control group was treated with conventional therapy, the observation group was treated with hyperbaric oxygen on the basis of control group.The efficacy, GOS, GCS, DRS and CD34+ in peripheral blood before and after treatment of twogroups were compared.Result:The total therapeutic efficiency of the observation group was82.50% significantly higher than control group of 60.00% (χ2=4.942, P=0.026).After treatment, the GCS score of the observation group was significantly higher than that of control group (t=5.221, P=0.000), the number of GOS>Ⅳ level was significantly higher than that of control group (χ2=14.459, P=0.000).The DRS score of the observation group was significantly lower than control group (t=2.822, P=0.000).After treatment 3-11 d, the CD34+ level in observation group was significantly higher than that before treatment (P<0.05), it was significantly higher than that of the control group in the same period (P<0.05).Conclusion:Hyperbaric oxygen treatment of brain trauma is effective and can effectively improve the level of CD34+ in peripheral blood
展开▼