Objective:To investigate the clinical application of caudal block combined with ketamine in pediatric abdominal operation. Method:68 patients in our hospital with lower abdominal operation were randomly divided into caudal block combined with ketamine group( observation group)and ketamine anesthesia group( control group),34 cases in each group,observed awake time,quantity of ketamine,anesthesia effect and adverse reaction. Result:Awake time and quantity of ketamine in observation group were lower than control group,the difference was statistically significant(P<0.05). Excellent and good rate of anesthesia in observation group was100%,significantly higher than that of control group 86.7%,the difference between groups was statistically significant(P<0.05). No Incidence of adverse reactions in observation group,in the control group the incidence of adverse reactions was 23.3%,the difference of incidence of adverse reactions between two groups was statistically significant(P<0.05). Conclusion:Caudal block combined with ketamine anesthesia used in pediatric abdominal operation has the advantages of simple operation,good effect of anesthesia,and a low incidence of adverse reactions,so it can be used as a safe and effective anesthetic methods for clinical using.% 目的：探讨骶管阻滞复合丙泊酚在小儿下腹部以下手术中的临床应用效果.方法：将本院60例下腹部手术患儿随机分为骶管阻滞复合丙泊酚(观察组)和氯胺酮复合丙泊酚麻醉组(对照组)，每组各30例，观察两组患儿清醒时间、氯胺酮用量、麻醉效果以及不良反应情况.结果：观察组患儿清醒时间及术中氯胺酮用量均少于对照组，差异有统计学意义(P<0.05).观察组麻醉效果优良率为100%，显著高于对照组的86.7%，组间差异有统计学意义(P<0.05).观察组未发生明显不良反应，对照组不良反应发生率为23.3%，不良反应发生率差异有统计学意义(P<0.05).结论：骶管阻滞复合氯胺酮麻醉应用于小儿下腹部手术操作简单，麻醉效果好，不良反应发生率低，因此可作为一种安全有效的麻醉方式在临床推广使用.
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