血浆脂联素检测在冠心病患者中的临床意义

摘要

Objective:To investigate clinical significance of the plasma adiponectin(APN)level in patients with coronary heart disease,and role in the development of coronary heart disease.Method:80 cases of patients with coronary heart disease,stable angina pectoris group of 45 cases,unstable angina group of 35 cases,30 cases of normal healthy people as a control group,plasma APN level,LDL-C,HDL-C were detected,and the results were analyzed.Result:In patients with coronary heart disease APN levels were significantly lower than those in the control group,the difference was statistically significant(P<0.05);unstable angina group APN level was lower than the stable angina group(P<0.05). Conclusion:Adiponectin may be a protective factor for coronary heart disease,and is negatively correlated with the development of coronary heart disease,also provide the clinical basis for the diagnosis of coronary heart disease.%　　目的：探讨血浆脂联素（APN）水平在冠心病患者中的临床意义，以及其在冠心病发生、发展中的作用。方法：选取确诊为冠心病患者共80例，其中稳定型心绞痛组45例，不稳定型心绞痛组35例，并且选取30例正常健康人作为对照组，检测血浆APN水平，同时检测LDL-C、HDL-C，并对检测结果进行分析。结果：冠心病患者APN水平明显低于对照组，两组比较差异有统计学意义（P<0.05）；不稳定型心绞痛组APN水平低于稳定型心绞痛组（P<0.05）。结论：脂连素可能为冠心病的一个保护因子，其与冠心病的发生发展呈负相关，为诊断冠心病提供了临床依据。