多潘立酮治疗慢性胃炎的临床疗效观察

摘要

Objective:To investigate the multi domperidone mitigation and improve the efficacy of the clinical symptoms of patients with chronic gastritis,and provide the basis for clinical application.Method:Selected 80 cases of patients with chronic gastritis in our hospital gastroenterology were randomly divided into two groups,each group had 40 cases.Two groups adopted different treatment,the control group were treated with famotidine,the observation group were treated with domperidone comparative analysis the treatment efficacy of two groups.Result:Two weeks after treatment,the control group total effective rate was 77.50%,the observation group total effective rate was 95.00%,compared the two groups was statistically significant(P<0.05);total symptom score in the two groups of patients before and after treatment,treatment one week and after two weeks and before treatment compared to the total score were statistically significant(P<0.05),compared to the observation group and the control group also statistically significant(P<0.05).Conclusion:Domperidone can significantly improve the clinical symptoms of patients with chronic gastritis,its mechanism may be related to gastric motion coordination,promote gastric emptying,it plays an important role in improving the quality of life of patients and guide clinical treatment.%　　目的：探讨多潘立酮缓解和改善慢性胃炎患者临床症状的疗效，为临床应用提供依据。方法：选取80例在本院消化内科接受治疗的慢性胃炎患者，随机分为两组，各40例。两组采用不同的治疗方案，对照组用药法莫替丁，观察组用药多潘立酮，对比分析两组的治疗疗效。结果：治疗两周后，对照组总有效率为77.50%，观察组总有效率为95.00%，两组比较差异具有统计学意义（P<0.05）；两组患者治疗前后症状总积分比较，治疗一周、两周后与治疗前总积分相比差异具有统计学意义（P<0.05），观察组与对照组比较差异也具有统计学意义（P<0.05）。结论：多潘立酮可以明显的改善慢性胃炎患者的临床症状，其作用机制可能与协调胃运动、促进胃排空有关，对提高患者生活质量和指导临床治疗具有重要作用。