目的：回顾性收集佛山地区老年症状性癫痫患者的临床资料，分析患者的病因并了解病因构成。方法：收集2004年7月1日-2014年7月1日在本院就诊的老年症状性癫痫病例526例，将症状性癫痫病因按脑外伤、围产期损伤、中枢神经系统感染、脑血管疾病、脑肿瘤、脑皮质发育畸形、神经皮肤综合征和其他病因进行分类。采用非参数分析的多样本秩和检验比较癫痫家族史和热性惊厥在癫痫病因中的作用及诊断价值。结果：526例老年症状性癫痫患者中，脑血管病158例（30.0%），脑外伤95例（18.1%），中枢神经系统感染63例（12.0%），脑肿瘤56例（10.6%），围产期损伤36例（6.8%），脑皮质发育异常30例（5.7%），神经皮肤综合征12例（2.3%），其他76例（14.5%）。癫痫家族史在神经皮肤综合征比例最高，而热性惊厥在脑皮质发育畸形中最高。结论：在本研究中发现，脑血管病、脑外伤、中枢神经系统感染、脑肿瘤、围产期损伤为老年症状性癫痫最主要的病因。%Objective:To retrospectively survey and explore the common causes of symptomatic epilepsy in elderly of Foshan. Method:526 cases of elderly symptomatic epilepsy were collected in our hospital from July 2004 to July 2014,who were arranged into different categories of head trauma,perinatal injuries,infection in central nervous system,cerebral vascular disease,brain tumor,disorder of cortical development,neurocutaneous syndrome and others. The role and value of diagnosis about symptomatic epilepsy were that the ferile seizure and family history were contrasted in different categories of cases by Kruskal-Wallis test. Result:In 526 cases,158 cases were cerebral vascular disease, 95 cases were head trauma,63 cases were infection in central nervous system,56 cases were brain tumor,36 cases were perinatal injuries,30 cases were disorder of cortical development,12 cases were neurocutaneous syndrome and 76 cases were others. Family history was the most frequent in neurocutaneous syndrome in symptomatic epilepsy,and febrile seizures was the most frequent in cases with disorder of cortical development in symptomatic cases. Conclusion:In the 526 cases,the main causes of them were cerebral vascular disease,head trauma,infection in central nervous system, brain tumor and perinatal injuries.
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