他汀类药物在急性冠状动脉综合征中的抗感染作用

摘要

Objective:To investigate the anti-infection effect of statins in acute coronary syndrome. Method:120 patients who carried out coronary stent implantation in our hospital were divided into control group and observation group. For observation group,statins treatment was performed after clopidogrel,while clopidogrel treatment was directly performed in control group. The effectiveness and safety were observed. Result:The total effectiveness of clinical treatment of observation group was 93.3%,which was significantly higher than 71.7%of the control group. After treatment,the troponin levels were lowered in both groups,while fall of the observation was much more evident. The occurrence of cardiovascular adverse reactions of the observation patients was 6.67%,which was significantly lower than that of control group. There were significant differences for indicators between the two groups. Conclusion:In order to improve the effectiveness,the treatment with statins in acute coronary syndrome needs further study.%目的：探讨他汀类药物在急性冠状动脉综合征中的抗感染作用。方法：采集本院收治的进行冠状动脉支架术后的120例患者，分为对照组和观察组，观察组先给予氯吡格雷后进行他汀类药物治疗，而对照组直接给予氯吡格雷药物治疗，观察期有效性及安全性。结果：观察组患者临床治疗的总有效率为93.3%，明显高于对照组的总有效率71.7%；两组患者治疗后，肌钙蛋白水平均下降，但是观察组患者下降更为明显；观察组患者心血管不良反应的发生率为6.67%，较对照组有明显降低，两组比较差异有统计学意义（P<0.05）。结论：他汀类药物在治疗急性冠状动脉综合征炎症的应用还需进一步研究，以提高治疗效果。