老年离退休人群血浆Hcy水平检测及与心血管疾病传统危险因素的相关分析

摘要

目的：探讨某地区离退休人群血浆中同型半胱氨酸（Hcy）水平的变化，探讨高Hcy血症与心血管疾病传统危险因素的关系，为老年人群健康体检预防心血管疾病提供理论依据和指导。方法：收集2013年十堰市地区东风公司离退休职工2200例血浆Hcy检测结果，按年龄与性别做分组统计。选取高Hcy血症人群分为高血压组、心电图异常改变组、吸烟组、高脂血症组、高血糖组。结果：本次老年体检人群高Hcy血症312例，占本次体检人群的14.18%，不同年龄组不同性别间的Hcy水平比较差异无统计学意义（P>0.05）；高血压组、心电图异常改变组、高脂血症组、高血糖组Hcy平均水平均高于健康对照组，差异有统计学意义（P<0.05）；高Hcy血症在高血压组发生率最高，其次为心电图异常改变组。结论：老年人群中高Hcy血症与心血管传统危险因素呈正相关，在健康体检中定期检测Hcy，对干预治疗老年人群心血管疾病有积极作用。%Objective:To discusses plasma homocysteine(Hcy)levels in the change of retired people of a region,to discusses the relationship between high Hcy levels and traditional risk factors of cardiovascular disease,provide theoretical basis and guidance,to prevent cardiovascular disease for elderly health check-up.Method:2200 cases of plasma Hcy results of retired worker of Shiyan dongfeng company in 2013 were grouped by age and gender did statistics;Selected high Hcy levels crowd were divided into high blood pressure,electrocardiogram(ecg)abnormal change,smoking,hyperlipidemia, hyperglycemia group.Result:312 cases of high Hcy levels of elderly check-up crowd,which accounted for 14.18%;The average Hcy levels between different age groups and different gender were no statistical significance(P>0.05);The average Hcy levels of high blood pressure,electrocardiogram(ecg) abnormal change group,hyperlipidemia,hyperglycemia group are higher than the healthy controls,the difference were statistically significant(P<0.05);The highest incidence of High Hcy levels was in hypertension group,followed by abnormal changes of electrocardiogram(ecg)group.Conclusion:High Hcy levels of the elderly and traditional cardiovascular risk factors are positively correlated,Hcy in healthy check-up regularly detection,produce positive effects on intervention in the treatment of elderly cardiovascular disease.