狼疮性肾炎患者并发院内感染病原菌分布及其危险因素分析

摘要

Objective:To analyze sore wolf nephritis patients with nosocomial infection pathogens and their risk factors,so as to get a better treatment method. Method:Eighty cases of sore wolf nephritis patients were chosen in our hospital from May 2009 to May 2012,and were observed the distribution of pathogens in patients with nosocomial infection,and the risk factors. Result:30 patients got nosocomial infection,the incidence rate was 37.5%. The fungal infection were 12 cases,accounting for 40% of infected patients. By risk factors analysis,relatively simple hormone therapy,combination therapy in the treatment of nosocomial incidence of fungal infection significantly increased,compared with others,the difference was statistically significant(P<0.05). Conclusion:In patients with lupus nephritis prone to fungal infection complicated with hospital,reducing hospitalization time,improvement of nutritional status,as well as proper treatment scheme are helpful to reduce hospitalization in patients with fungal infection.%目的：探讨狼疮性肾炎患者并发院内感染病原菌分布及其危险因素分析，以致获取更好的治疗手段。方法：选取本院2009年5月-2012年5月收治的80例狼疮性肾炎患者进行研究，观察患者院内感染病原菌分布，以及其感染的危险因素。结果：80例患者有30例患者发生院内感染，发生率为37.5%。其中真菌感染12例，占感染患者的40.0%。经危险因素分析发现，相对单纯激素治疗，联合治疗发生院内真菌感染的发生率显著增高，比较差异有统计学意义（P<0.05）。结论：狼疮性肾炎患者易并发院内真菌感染，减少住院时间，营养状况的改善，以及适当的治疗方案有助于降低住院患者真菌感染的发生。