Objective:To study the effect of two methods of diaper creams and sanguisorba oil to prevent crissum skin damage from enternal nutrition cid-associated diarrhea in ICU.Method:From June 2012 to June 2013,there were 80 ICU patients with enternal nutrition cid-associated diarrhea chosen in our study. They were randomly divided into two groups. One group was treated with diaper creams,and the other group was treated with sanguisorba oil.Each group enrolled 40 patients separately.The two groups of patiens were treated according to operational standard. Observed and compared the incidence,occurrence time and severity of crissum skin damage.Result:The incidence of crissum skin damage of patients treated with diaper creams was 40.0%(16/40), and patients treated with sanguisorba oil was 12.5%(5/40).The difference was significant(P<0.05).The occurrence time of crissum skin damage of patients treated with diaper creams was (2.46±1.95)d and patients treated with sanguisorba oil was (2.13±1.21)d.The occurrence time of crissum skin damage in two groups was no significant difference.The degree of crissum skin damage of patients treated with diaper creams was (3.29±0.52)points and patients treated with sanguisorba oil was (1.39±0.15)points.The degree of crissum skin damage of patients treated with diaper creams was significantly higher than patients with sanguisorba oil (P<0.05).Conclusion:The treatment of sanguisorba oil can reduce the incidence and severity of skin damage,which is effective method to prevent crissum skin damage caused by enternal nutrition cid-associated diarrhea.%目的：观察并比较外涂护臀霜和地榆油对肠内营养相关性腹泻ICU患者肛周皮肤损伤的预防效果。方法：选择本院2012年6月-2013年6月收治的80例表现出肠内营养相关腹泻的ICU患者，根据处理方式的不同分为护臀霜组和地榆油组，每组40例患者。按照操作规范对两组患者进行处理。观察并比较两组患者肛周皮损发生率、发生时间及严重程度，以评价护理效果。结果：外涂护臀霜组肛周皮肤损伤发生率为40.0%（16/40），地榆油组为12.5%（5/40），差异具有统计学意义（P<0.05）；外涂护臀霜组肛周皮肤出现损伤的时间为（2.46±1.95）d，地榆油组为（2.13±1.21）d，差异无统计学意义。外涂护臀霜组皮损严重程度评分为（3.29±0.52）分，地榆油组为（1.39±0.15）分，差异有统计学意义（P<0.05）。结论：对于出现肠内营养相关性腹泻的ICU患者，外涂地榆油可以降低患者肛周皮肤损伤率，减轻皮肤损伤程度，有效预防肛周皮肤损伤。
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