冠心病患者心率变异性和Q-T离散度临床研究

摘要

Objective:To reseach the clinical character of the heart rate variability(HRV)and QT dispersion in the patients with coronary heart disease(CHD).Method:The patients with coronary heart disease by coronary angiography confirmed(CHD group,n=78)and normal coronary angiography examiners(control group,n=64)were chosen and given 24 h dynamic electrocardiogram monitoring.The parameters of HRV and QT dispersion were calculated, and the features of these parameters were compared and analyzed between the two groups.Result:HRV(SDNN, SDANN,RMSSD,pNN50,TP and HF )decreased in CHD group compared with control group(P<0.05),while QT dispersion prolonged in CHD group compared with control group(P<0.01).Conclusion:HRV is decreased and QT dispersion is prolonged in CHD patients.%目的：研究冠状动脉粥样硬化性心脏病（冠心病）患者心率变异性（HRV）和Q-Tc离散度的临床特点。方法：入选78例确诊的冠心病患者为冠心病组，入选64例冠状动脉造影正常的为对照组，所有研究对象均进行24 h动态心电图监测，对两组的心率变异性和Q-Tc离散度指标进行统计学分析。结果：冠心病组的心率变异性指标SDNN、RMSSD、pNN50、SDANN较对照组明显降低，Q-Tc离散度较对照组明显延长，差异具有统计学意义（P<0.05）。结论：冠心病患者心率变异性明显降低，Q-Tc离散度明显延长。