龙胆泻肝汤联合金黄散治疗急性附睾炎的疗效观察

摘要

目的：观察龙胆泻肝汤联合金黄散治疗急性附睾炎的临床疗效。方法：选取急性附睾炎患者62例，采用龙胆泻肝汤联合金黄散治疗4周。评价治疗前后的视觉模拟（visual analogue scale，VAS）疼痛评分和中医症候积分，并观察治疗前后附睾大小和彩色多普勒血流显像（colour doppler flow imaging， CDFI）血流分级变化。结果：治疗后患者VAS疼痛评分[（2.20±1.03）分vs（6.40±1.51）分]和中医症候积分[（3.40±2.01）分vs（8.30±1.49）分]较治疗前均降低（t=7.324、5.683，P=0.000）；治疗后附睾大小较治疗前降低[头厚：（1.48±0.37）cm vs（0.87±0.33）cm，t=3.227，P=0.010；体厚：（0.76±0.21）cm vs （0.47±0.10）cm，t=3.764，P=0.004；尾厚：（1.70±0.29）cm vs （0.88±0.24）cm， t=4.973，P=0.001]；CDFI血流分级较治疗前改善，且治疗后Ⅰ级、Ⅱ级和Ⅲ级所占比率与治疗前比较，差异均有统计学意义（χ²=14.583、9.197、37.681，P=0.000、0.004、0.000）。结论：龙胆泻肝汤联合金黄散治疗急性附睾炎临床效果良好，可降低附睾的大小，并改善其血流分级。%Objective:To observe the clinical effects of Longdan Xiegan Decoction combine with Jinhuang Powder on patients with acute epididymitis.Method:A total of 62 patients with acute epididymitis using Longdan Xiegan Decoction combine with Jinhuang Powder for 4 weeks.Visual analogue scale (VAS) pain score and Chinese medicine symptom complex score were evaluated before and after treatment. Meanwhile, the size of epididymis and the change of colour doppler flow imaging(CDFI) before and after treatment were observed and compared. Result:The scores of VAS pain[(2.20±1.03)scores vs (6.40±1.51)scores] and Chinese medicine symptom complex [(3.40±2.01)scores vs (8.30±1.49)scores] were lower after treatment than before treatment(t=7.324, 5.683,P=0.000).The size of epididymis were lower after treatment than before treatment [caput:(1.48±0.37)cm vs (0.87±0.33)cm,t=3.227,P=0.010;body:(0.76±0.21)cm vs (0.47±0.10)cm,t=3.764,P=0.004;tail:(1.70±0.29)cm vs (0.88±0.24)cm,t=4.973,P=0.001].The levels of CDFI were change better than before treatment,and compared with before treatment,there were significant differences in the ratio of class Ⅰ, class Ⅱ and class Ⅲ between before and after treatment( χ²=14.583,9.197,37.681,P=0.000,0.004,0.000). Conclusion:The effect of Longdan Xiegan Decoction combine with Jinhuang Powder on patients with acute epididymitis is good,and it can reduce epididymis size,change degree of blood flow.