妇科恶性肿瘤腹腔镜手术后下肢深静脉血栓形成的危险因素分析

摘要

Objective To explore the risk factors of deep venous thrombosis in lower limbs (LDVT) following laparoscopic surgery for gynecologic malignancies. Methods The clinical data of 242 cases of gynecological malignant tumor in laparoscopic operation were collected. The correlation between the operation mode, operation time, body mass index (BMI), age, hypertension, diabetes, serum triglyceride (TG), cholesterol (CHOL) and postoperative LDVT formation by using univariate analysis and logistic multivariate regression analysis. Results The incidence of LDVT among the total cases was 22 patients during hospitalization and the incidence rate was 9.09%. Univariate analysis and logistic multivariate regression analysis showed age , hypertension , diabetes , extensive hysterectomy subtotal + double attachment + pelvic lymph node dissection , operation time >3 hours were the risk factors for the formation of LDVT (P<0.05). Conclusion Gynecological malignant tumor after laparoscopic operation is prone to LDVT. Clinical risk factors in patients with predisposing factors taking active intervention is very necessary.%目的：探讨妇科恶性肿瘤腹腔镜手术后下肢深静脉血栓（LDVT）形成的危险因素。方法收集242例妇科恶性肿瘤行腹腔镜手术临床资料，应用单因素及 Logistic 多因素回归分析手术方式、手术时间、体重指数（BMI）、年龄、高血压、糖尿病、甘油三酯（TG）、胆固醇（CHOL）与术后LDVT 形成有无相关性。结果全组共22例患者住院期间发生LDVT，发生率为9．09％。单因素及Logistic 多因素回归分析显示年龄、高血压、糖尿病、广泛全子宫＋双附件切除＋盆腔淋巴结清扫术、手术时间＞3小时是影响LDVT 形成的危险因素（P＜0．05）。结论妇科恶性肿瘤行腹腔镜手术后易发生LDVT ，临床上对合并易患因素的患者采取积极的干预措施非常必要。