Objective: To evaluate the clinical diagnosis value of CT-guided percutaneous core needle lung biopsy. Methods: The clinical data of 85 patients with thoracic nodules/masses underwent CT-guided percutaneous core needle lung biopsy were retrospectively analyzed from Feb.2003 to Feb 2012. Results: The sensitivity, specificity, positive prediction value and negative prediction value for the diagnosis of malignant lesions were 95.9%, 100%, 100%, 80% respectively. The accuracy of diagnosis was 95. 3%. The incidence of complicated pneumothorax and pulmonay hemorrhage were 9.4% and 3.5% respectively. Conclusion: CT-guided percutaneous needle lung biopsy is a safely diagnostic technology in thoracic masses with high accuracy and low incidence of complication.% 目的：探讨CT导引下经皮穿刺切割活检对胸部肿块的诊断价值.方法：回顾性分析2003年2月-2012年2月85例胸部肿块患者行CT导引下经皮穿刺切割活检术的临床资料.结果：经皮穿刺切割活检组织经病理学诊断85例，穿刺活检诊断恶性肿瘤的灵敏度为95.9%、特异度为100%，阳性预测值为100%，阴性预测值为80%，穿刺活检诊断正确率为95.3%.气胸发生率为9.4%，出血发生率为3.5%.结论：CT导引下经皮穿刺切割活检诊断正确率高，并发症轻，是一种安全准确的检查方法.
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