Objective To investigate the nutrition therapy combined with psychological intervention on the treatment of gestational diabetes mellitus .Methods 200 patients with pregnancy in gestational diabetes were ran‐domly divided into observation group and control group with 100 cases in each .The control group was given conven‐tional treatment of gestational diabetes mellitus ,while the observation group was given uutrition therapy combined with psychological intervention based on the control group .The blood biochemical index ,maternal complications ,ce‐sarean section and neonatal outcomes were compared before and after treatment .Results The fasting blood glucose , glycosylated hemoglobin ,C‐reaction protein were (5 .47 ± 0 .51) mmol/L ,(5 .93 ± 0 .54)% ,(10 .89 ± 2 .87) mg/L in the observation group after treatment ,it was significantly lower than that before treatment ,the difference was statis‐tically significant (P< 0 .05) .The pregnancy induced hypertension ,premature rupture of membranes ,polyhydram‐nios ,premature delivery ,cesarean section and macrosomia ,fetal distress ,neonatal asphyxia of the observation group were significantly lower than the control group ,the difference was statistically significant (P<0 .05) .Conclusion Nutrition therapy combined with psychological intervention can help patients with gestational diabetes blood sugar control .%目的：探讨营养综合治疗联合心理干预对妊娠期糖尿病的临床疗效。方法妊娠期糖尿病患者200例，采用随机数字表法分为观察组和对照组，各100例，对照组给予产科妊娠期糖尿病的常规治疗，观察组在此基础上给予营养综合治疗联合心理干预，比较2组治疗前后的血液生化指标、产妇并发症、剖宫产率及新生儿状况。结果观察组31例患者、对照组81例患者进行胰岛素治疗，差异有统计学意义（ P＜0．05）。治疗后观察组患者的空腹血糖、糖化血红蛋白、C‐反应蛋白分别为（5．47±0．51）mmol／L、（5．93±0．54）％、（10．89±2．87）mg／L ，显著低于治疗前和对照组治疗后的相应指标，差异均有统计学意义（P＜0．05）。观察组的妊高征、胎膜早破、羊水过多、早产、剖宫产和巨大儿、胎儿宫内窘迫、新生儿窒息等发生率明显低于对照组，差异有统计学意义（P＜0．05）。结论营养综合治疗联合心理干预对妊娠期糖尿病患者具有临床意义。
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