目的：观察比较3种不同封闭剂的体外抑菌性能：氧化锌丁香油封闭剂、环氧树脂类封闭剂（下称AH Plus）、生物陶瓷类封闭剂（下称iRoot SP）的体外抑菌性能。方法采用琼脂扩散法，选取粪肠球菌、金黄色葡萄球菌、白色念珠菌作为实验菌种。在37℃温箱观察24 h后检测各组材料抑菌环的大小，评估其抗微生物的作用。结果氧化锌丁香油组对于3种实验菌均有良好的抑制作用，产生的抑菌区域极显著于 AH Plus组及iRoot SP组（P＜0．01）。AH Plus组与iRoot SP组对于粪肠球菌差异有统计学意义（P＜0．01）；对白色念珠菌抑菌效果差异有统计学意义（P＜0．05）；对于金黄色葡萄球菌抑菌效果差异无统计学意义（P＞0．05）。结论 iRoot SP虽然具备了一个优良封闭剂所需的诸多优点，但琼脂扩散实验显示其抑菌性能方面还有待加强。%Objective To observe antimicrobial activity of three types of root canal sealers .Methods Agar diffusion test .We selected Enterococcus Faecalis (E .faecalis) ,Staphylococcus aureus(S .aureus) ,Candida albicans (C .albicans) ,as experimental strains .We put these strains in an incubator at 37 ℃ .After 24 hours ,we observed the radius of bacteriostatic circle of Zinc Oxide Eugenol sealer(ZOE);AH Plus and iRoot root canal sealing paste(iRoot SP) ,respectively .Results ZOE has good inhibitory effect on the three kinds of experimental bacteria ,while the re‐gion has a highly significant statistical inhibition than AH Plus and iRoot SP(P<0 .01) .there were extremely statis‐tical difference for E .faecalis among the zones of inhibition of microbial growth of AHPlus and iRoot SP(P<0 .01);there also have statistical difference for C .albicans among AHPlus and iRoot SP(P<0 .05);No statistical difference for S .aureus antibacterial effect(P>0 .05) .Conclusion Antibacterial performance of new type of biological ceramic material iRoot SP needs to be strengthened by ADT experiments showing .
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