慢性乙型肝炎中医证型与检验医学指标相关性分析

摘要

Objective To observe the relationship between chronic hepatitis B (CHB) Tradition Chinese Medicine(TCM ) types and clinical test indexes .Methods From Aug .2014 to Jan .2015 ,patients with CHB ,meeting the inclusion criteria ,were divided in‐to blood stasis syndrome group ,liver syndrome group ,damp heat syndrome group and liver and gallbladder damp heat syndrome group ,according to related TCM diagnosis standards .Serum biochemical parameters were compared between all groups .Results Albumin(Alb) and pre‐albumin(PA) levels in blood stasis syndrome group were lower than damp heat syndrome group (P<0 .05) . Indirect bilirubin(IBil) ,Alb and PA levels in liver syndrome group were lower than damp heat syndrome group and liver and gall‐bladder damp heat syndrome group(P<0 .05) .Albumin/Globulin(Glo) ratio(A/G) in liver syndrome group was lower than damp heat syndrome group(P< 0 .05) .Creatinine(CREA) level in damp heat syndrome group was higher than the other groups(P<0 .05) .Totla bilirumin(TBil) ,IBil ,Alb and PA levels in damp heat syndrome group were higher than liver syndrome group ,but Glo level was lower(P<0 .05) .Conclusion Liver function in blood stasis syndrome and liver syndrome patients could be lower than damp heat syndrome patients .Elevated bilirubin might be mainly in damp heat syndrome patients .%目的：探讨慢性乙型肝炎（简称乙肝）中医证型与检验医学指标的相关性。方法根据中医证型相关诊断标准，于2014年8月至2015年1月将符合入选标准的慢性乙肝患者分为血瘀证组、肝郁证组、湿热证组和肝胆湿热证组，分析各组间肝功能、肾功能及血脂指标水平。结果血瘀证组清蛋白（Alb）、前清蛋白（PA）水平低于湿热证组（P＜0．05）。肝郁证组间接胆红素（IBil）、Alb和PA水平低于湿热证组和肝胆湿热证组（P＜0．05）。肝郁证组清蛋白／球蛋白比值（A／G）低于湿热证组（P＜0．05）。湿热证组A／G水平低于肝胆湿热证组（P＜0．05）。湿热证组肌酐（CREA）水平高于血瘀证组、肝郁证组和肝胆湿热证组（P＜0．05）。湿热证组总胆红素（TBil）、IBil、Alb、PA、A／G水平高于肝郁证组，球蛋白（Glo）水平低于肝郁证组（P＜0．05）。结论血瘀证、肝郁证慢性乙肝患者肝脏代谢功能弱于湿热证患者。胆红素水平升高多见于湿热证患者。