目的 探讨球后注射氯丙嗪对绝对期青光眼患者血压水平、止痛效果及不良反应的影响.方法 选取该院2014年5月至2016年5月收治的绝对期青光眼患者80例(80眼),随机将这些患者分为球后注射氯丙嗪组(40例,40眼)和睫状体冷凝术组(40例,40眼),对两组患者的血压水平、眼压水平、止痛效果及不良反应发生情况进行统计分析.结果 球后注射氯丙嗪组患者的舒张压、收缩压水平均明显高于睫状体冷凝术组,差异有统计学意义(P<0.05);眼压水平明显低于睫状体冷凝术组,差异有统计学意义(P<0.05);眼痛、头痛消失率为75.0%(30/40),明显高于睫状体冷凝术组的30.0%(12/40),差异有统计学意义(P<0.05);不良反应发生率为32.5%(13/40),明显低于睫状体冷凝术组的55.0%(22/40),差异有统计学意义(P<0.05).结论 球后注射氯丙嗪能够有效维持绝对期青光眼患者的血压水平,提升止痛效果,减少不良反应.%Objective To investigate the effects of retrobulbar injection of chlorpromazine on blood pressure level,analgesic effect and adverse reactions in the patients with absolute glaucoma.Methods Eighty cases of absolute glaucoma(80 eyes) in our hospital from May 2014 to May 2016 were selected and randomly divided into the retrobulbar injection of chlorpromazine group(n=40,40 eyes) and cyclocryosurgery group(n=40,40 eyes).The blood pressures,intraocular pressure levels,analgesic effects and adverse reactions of the two groups were statistically analyzed.Results The diastolic blood pressure,systolic blood pressure levels in the retrobulbar injection of chlorpromazine group were significantly higher than those in the cyclocryosurgery group,the difference was statistically significant(P<0.05),the intraocular pressure level was significantly lower than that in cyclocryosurgery group with statistical difference(P<0.05),the eye pain,headache disappeared rate was 75.0%(30/40),which was significantly higher than 30.0%(12/40) in the cyclocryosurgery group(P<0.05),the incidence rate of adverse reactions was 32.5%(13/40),which was significantly lower than 55.0%(22/40) in the cyclocryosurgery group(P<0.05).Conclusion Retrobulbar injection of chlorpromazine can effectively maintain the blood pressure level,enhances the analgesic effect,and reduces adverse reactions in the patients with absolute glaucoma.
展开▼
