2型糖尿病患者运动后心率恢复与运动能力的研究

摘要

目的 了解2型糖尿病(T2DM)患者运动后心率恢复(HRR)情况,探讨其与运动能力的相关性. 方法入选经症状限制性心肺运动试验(CPET)结果为阴性的T2DM患者27例(试验组),门诊健康体检者36例(对照组). 测定运动试验后1~4 min心率恢复指标( HRRT)及运动能力指标. 结果 试验组HRRT明显低于对照组,差异均具有统计学意义(P<0.01);峰值心率、峰值摄氧量(Peak VO2/kg)、峰值代谢当量(Peak METs)和心率储备(HRRes)也低于对照组,差异均具有统计学意义(P<0.01);静息心率高于对照组(P<0.05). 所有受试者运动后1 min心率恢复值(HRR1)与Peak VO2/kg、Peak METs和HRRes均呈正相关(r值分别为:0.40、0.35、0.55,均P<0.01). 结论 T2DM患者运动后心率恢复减慢、运动能力降低,且运动能力同心率恢复呈正相关.%Objective To assess the heart rate recovery (HRR) of type 2 diabetes mellitus (T2DM) patients after exercises testing and investigate its relationship with mobility.Methods A total of 27 patients who produced negative re-sults after symptom-limited cardiopulmonary exercise testing ( CPET) ( the treated group) and 27 healthy subjects ( the control group) were enrolled in to the current study.Then the heart rate recovery time ( HRRT) and mobility index were measured after testing.Results The treated patients had obviously shorter HRRT than the control (P<0.01), de-creased peak heart rates, Peak VO2/kg, Peak METs and heart rate restorations ( HRRes) , but higher resting heart rates, compared with the control (P<0.05).All participants presented the values of 1-minute heart rate recovery (HRR1) after exercises which was positively correlated with Peak VO2/kg (r=0.40, P<0.01), Peak METs (r=0.35, P<0.01) and HRRes (r=0.55, P<0.01).Conclusion T2DM patients show slower heart rate recovery and reduced mobility, and a positive correlation exists between them.