创伤后多器官功能衰竭危险因素预测性比较

摘要

目的　研究及预测创伤后多器官功能衰竭的危险因素，以 探讨其预测模式。方法　随机抽样选取创伤后存活时间＞48小时以上的严 重创伤病人578例，其中44例发生MOF。采用AIS-ISS、APS-APACHE及BD等相关指标对伤员 的组织损伤、生理参数、伤前状况、临床因素进行分析对比。结果　MOF所 表现出的早期和后期性的双峰现象与损伤程度、休克、感染、高龄以及伤前有无慢性疾 病等因素有关，且提示应用量化指标可增加其预测性。结论　单变量指标 多难以提高MOF预测性，需建立致衰性组合的预测模式%Objective　To investigate predictive power of de veloping MOF risk factors in trauma patients.Methods　The clinic al date of 578 trauma patients surviving＞48 hours after injury were studied,am ong them 44 cases developed MOF.The data of the cases were analyzed and contra sted by indicators of AIS-ISS,APS-APACHE Ⅲ and BD in tissue injury,physiolog ic parameters,preexisting health conditions and clinic factors.Results　 The bimodal phenomenon in early MOF versus late MOF were related to fact ors of severity,shock,infection,venerable age and comorbid diseases,and it showe d that the predictive power was added with measuring indicators.Conclu sion　The posttrauma MOF was difficult to be predicted by a single varia ble indicator.The predictive model should be built in the constitution of causi ng MOF.