利伐沙班对合并糖尿病的老年股骨粗隆间骨折术后下肢深静脉血栓形成的预防

摘要

Femoral intertrochanteric fracture is a common type of hip fracture in clinical trauma surgery.Elderly femoral intertrochanteric fracture patients combined with diabetes mdlitus usually require a period to keep lying in bed for forbiding activity in the perioperative period. This condition leads to high risk of deep vein thrombo sis,which is a complication with high disability and high mortality rate. More seriously,the deep vein thrombosis can be secondaty to the ptdmonary thromboembolism ( PTE }. Rivaroxaban gradually becomes the new oral intake of anticoagtdant for the aged diabetes mellitus patients after the orthopaedics operation because of many advantages such as convenient application, no requirement of determining coagnlation function, lower interaction with others medicines and food,and reliable anticoagtdation.%股骨粗隆间骨折是创伤骨科常见髋部骨折类型.合并糖尿病的老年股骨粗隆间骨折患者在围手术期需要一定时期的卧床制动,由于合并基础疾病往往具有较高的下肢深静脉血栓(deep vein thrombosis,DVT)形成的风险性,而DVT又是此类患者围手术期致残率、致死率较高的并发症之一,严重者可继发致死性肺动脉血栓栓塞症 (PTE).利伐沙班因其应用方便、无须常规检测凝血功能、与药物及食物相互作用少以及具有可靠的抗凝作用等优点,逐渐成为老年糖尿病患者创伤骨折术后预防DVT形成的新型口服抗凝药物.