面孔表情加工的事件相关电位研究及应用

摘要

目的探讨面孔表情诱发的事件相关电位(ERP)时空模式特点.方法25名受试者从事简笔画面孔表情识别任务.实验采用单因素(三水平:正性、中性、负性表情)重复测量析因设计和双侧配对t检验进行逐对比较(Bonferroni校正),利用统计参数映像呈现结果.结果显著的表情效应分别于3个时段出现在不同的头皮区域:后顶区和双枕区(280～340ms),左额区(40～420ms)和右额区(48～500ms).正性与中性表情的差异分别于4个时段相继出现在不同的头皮区域:右额顶颞区和左前额区(60～80 ms),右枕区(120～140ms),左枕区(280～320 ms)和左额顶区(400～440 ms).负性与中性表情的差异分别于5个时段相继出现在不同的头皮区域:右枕区(120～140ms),中央额顶区(220～240ms),中央顶区(280～300ms),左顶和右额颞区(320～340ms)和额顶枕颞区(480～500ms).结论面孔表情加工是涉及广泛脑区的动态演化过程,不同情绪的脑加工通路是不同的.%Objective To investigate spatial and temporal patterns of event-related potentials (ERP) evoked by facial expression.Methods ERP was recorded in 25 healthy subjects while they performed facial recognition task. Repeated-measure one-way ANOVA was adopted to compare the subjects' responses to stimulation by 3 different expressions (positive, neutral and negative) with statistical parametric mapping (SPM). Results Significant facial expression effects occurred separately in the left parietal and bilateral occipital regions (280-340 ms), left frontal region (400-420 ms), and right prefrontal region (480-500 ms).In 4 time periods, significant difference was observed between positive and neutral emotion wave in the right frontoparietotemporal and left prefrontal regions (60-80 ms), right occipital region (120-140 ms), left occipital region (280-320 ms), and left frontoparietal region (400-440 ms). Significant difference between negative and neutral emotion waves was observed in 5 time periods in the right occipital region (120-140 ms), central frontoparietal region (220-240 ms), central parietal region (280-300 ms),left parietal and right temporopartial regions (320-340 ms) and frontopartial occipitotemporal region (480-500 ms).Conclusions The spatiotemporal patterns of ERP suggest that the information processing of facial expression involves extensive brain regions dynamically.