With the development of the nanoparticles and molecular imaging , the multifunctional nanoparticles have responded to the needs of current clinical medicine .More and more nanoparticles have used in experimental research such as albumin nanoparticles , liposomes , magnetic materials and carbon nanoparticles .With the combi-ning radionuclide with multifunctional nanoparticles , the nanoparticles have the advantages of small size , slow re-lease and surface modification , so that the therapeutic effect of radionuclides can efficient .Not only it can reduce the toxic and side effects of the radionuclides , but also improve the therapeutic efficiency and target concentration . With nanotechnology as the core , the integration of biomedical treatment and molecular imaging in diagnosis and treatment will become a new way of clinical medicine development in the future .%随着纳米技术和分子影像学的发展,多功能纳米载体系统响应了目前临床医学以及基础医学的需求.白蛋白纳米载体、脂质体纳米载体、磁性材料纳米载体以及碳纳米载体等是目前研究的较多的纳米载体.将放射性核素与多功能纳米载体相结合,利用纳米载体的粒径小、缓释性以及表面可修饰性等特点可将放射性核素本身的治疗效果发挥至最佳.不仅可以减少放射性核素的毒副作用,而且可以提高放射性核素的治疗效率和靶向浓度.以纳米技术为核心,将生物医学治疗和分子影像学相结合的诊断治疗一体化新模式将成为未来临床医学发展的新思路.
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