Objective To investigate the efficacy of hysteroscopy combined with guidewire intervention in the treatment of oviduct ob-struction. Methods Clinical data of 326 cases treated with hysteroscopy combined with guidewire intervention were retrospectively analyzed. Results The total effective rate was 81. 0%. The effective rate for isthmus obstruction, interstitial and ampulla obstruction and umbrella obstruction patients was 89. 8%, 86. 0% and 51. 5%, respectively. The patients were followed up for 1 year after the op-eration and the pregnancy rate was 43. 8%, 47. 2% and 8. 8%, respectively. The total intrauterine pregnancy rate was 32. 5%(106/326). Conclusion Hysteroscopy combined with guidewire intervention in the treatment of oviduct obstruction is a safe, effective, simple and minimally invasive method, especially for the obstruction in interstitial tube and isthmus.%目的：探讨宫腔镜联合导丝介入治疗输卵管梗阻的临床效果。方法回顾性分析326例输卵管梗阻患者采用宫腔镜联合导丝介入治疗的临床效果。结果326例输卵管梗阻患者总有效率81.0%。输卵管峡部、间质部和壶腹部及伞部梗阻患者有效率分别为89.8%,86.0%和51.5%,术后随访1年宫内妊娠率分别为43.8%,47.2%和8.8%,宫内总妊娠率为32.5%(106/326)。结论宫腔镜联合导丝介入治疗是目前诊治输卵管梗阻性不孕安全、有效、简单的一种微创治疗方法,尤其适用于输卵管间质部和峡部阻塞的治疗。
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