Orthopaedic Laboratory Orthopaedics and Traumatology Hospital Qingdao 266003 China;
Department of Orthopaedic Surgery Affiliated Hospital of Medical College Qingdao University Qingdao 266003 China;
Department of Orthopaedic Surgery Affiliated Hospital of Medical College Qingdao University Qingdao 266003 China;
adeno-associated virus; adenovirus; transforming growth factor β1; nucleus pulpous proteoglycan;