Objective Lately, microwave radiation (MR) has been successfully used to cure a variety ofdiseases including oral mucosal diseases and oral tumors in stomatology. Preventive MR of precancerous lesionsfrom canceration is the goal of this study which had been rarely reported. Methods Between leukoplakia modelanimals and MR treated model animals, the cancer incidences were compared and the macroscopic and microscopicpathology were detailed. The functional parameters of the microwave apparatus were analysed to yield the optimumdata for future clinical use. Results The cancer blocking effect of MR was proved by the incidence of canceration3.5 times less frequent in MR treated animals. Conclusion Analysis of the macroscopic and microscopicpathology may disclose the mechanism of the therapeutic MR.
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