七氟醚吸入麻醉在全胃切除手术中的应用

摘要

目的 探讨七氟醚吸入麻醉在全胃切除手术中的临床应用价值.方法 回顾性分析我院2010年3月至2012年3月76例行全胃切除术患者的临床资料,按不同麻醉方法分成2组,每组38例.对照组给予靶控输注丙泊酚复合舒芬太尼麻醉,实验组给予吸入七氟醚复合舒芬太尼麻醉.观察比较2组患者的麻醉恢复情况、脑电双频指数(BIS)和血流动力学变化情况、术后疼痛评分及不良反应发生情况.结果 实验组患者的定力恢复时间、随意运动恢复时间均明显少于对照组(P＜0.05)；2组患者麻醉后(T1 ～T5时段)的BIS、收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)指标水平与麻醉前(T0时段)相比均明显降低(P＜0.05),实验组患者T1 ～T5时段的心率指标水平较对照组稳定(P＜0.05)；实验组患者的术后疼痛评分和不良反应总发生率明显低于对照组(P＜0.05).结论 全胃切除手术中采用吸入七氟醚复合舒芬太尼麻醉的临床效果良好.%Objective To investigate the clinical value of sevoflurane inhalation anesthesia in the total gastrectomy. Methods The 76 cases of row total gastrectomy patients in our hospital from March 2010 to March 2012 were randomly divided into the control group (n = 38) and the treatment group (n = 38). The control group was given target-controlled infusion of propofol combined with sufentanil anesthesia, while the treatment group was given sevoflurane inhalation anesthesia. The anesthesia recovery, changes of bispectral index and hemodynam-ic, the postoperative pain scores and adverse reactions were compared. Results The recovery time of abstraction power and voluntary movement in the treatment group were significantly shorter than that of the control group (P <0. 05) ; the BIS、SBP、DBP、MAP index value of T1 ~T5 in the treatment group were significantly lower than the index value of T0, the HR index value of T1 ~ T5 in the treatment group were significant sexual stable than the control group (P <0. 05) ; the postoperative pain scores in the treatment group were significantly lower than the control group (P<0.05) ; the total incidence of adverse reactions in the treatment group were significantly less than the control group (P <0.05). Conclusion There is a significant clinical value of sevoflurane inhalation anesthesia in the total gastrectomy.