乳腺癌患者手术治疗前后血清CA15-3、CA50和M-CSF检测的临床意义

摘要

Objective To explore the clinical significance of changes on serum CA15-3 , CA50 and M-CSF levels after surgery in patients with breast cancer.Methods Serum CA15-3, CA50 and M-CSF concentration from patients with breast cancer and healthy normal controls were determined by BIA.Results Before operation, the serum CA15-3,CA50 and M-CSF levels in the patients with breast cancer were significantly higher than those in controls (P0.05) .Conclusion Detection of serum CA15-3 , CA50 and M-CSF levels after operation might be of prognostic importance in patients with breast cancer.%目的:探讨了乳腺癌患者手术治疗前后血清CA15-3、CA50和M-CSF水平的变化及临床意义.方法:应用放射免疫分析对32例乳腺癌患者进行了手术治疗前后血清CA15-3、CA50和M-CSF检测,并与35名正常健康人作比较.结果:乳腺癌患者在手术治疗前血清CA15-3、CA50和M-CSF水平均非常显著地高于正常人组(P0.05).结论:检测血清CA15-3、CA50、M-CSF水平的变化对乳腺癌的诊断、治疗和预后观察均具有重要的临床价值.