非药物治疗对恢复期精神分裂症患者认知功能影响的对照研究

摘要

目的 探究非药物治疗对恢复期精神分裂症患者认知功能的影响.方法 将130例恢复期精神分裂症患者随机分为研究组和对照组各65例.对照组在常规药物治疗基础上实施一般护理干预,研究组在药物治疗的同时使用非药物治疗,采用阳性和阴性综合征量表(PANSS)于干预后第12周末对精神病症状进行评定,采用可重复成套神经心理状态测量表(RBANS)、威斯康星卡片分类测验(WCST)评定其认知功能.结果 研究组干预后第12周末PANSS总分及各因子分均较入组时降低(P＜0.01),且均低于对照组(P＜0.01).研究组干预后第12周末RBANS总分及各因子分均较入组时升高(P＜0.01),且均高于对照组(P＜0.01).研究组干预后第12周末WCST总应答数、持续错误数、随机错误数均较入组时降低(P＜0.05),正确应答数、完成分类数均较入组时升高(P＜0.05);研究组干预后第12周末WCST总应答数、持续错误数、随机错误数均低于对照组(P＜0.05),正确应答数、完成分类数均高于对照组(P＜0.05).结论非药物治疗对改善恢复期精神分裂症患者的认知功能有明显的效果.%Objective To explore the effect of non-drug treatment on cognitive function in convalescent schizophrenic patients.Method 130 schizophrenic patients at convalescence were randomly divided into the study group and the control group each with 65 cases.The control group performed general nursing interventions on the basis of conventional drug therapy.The study group used non-drug treatments at the same time as drug treatment.Positive and Negative Syndrome Scales (PANSS) were used to assess psychotic symptoms on the 12th week after intervention.Repeated sets of Neuropsychometrics ( RBANS) and Wisconsin Card Sorting Tests (WCST) assessed cognitive function.Results At the end of the 12th week, the PANSS total scores and each factor score in the study group were lower than those in the group after intervention (P＜0.01), and were lower than those in the control group ( P＜0.01).After the intervention of the study group , the total score and the factor score of RBAS at the 12th week were higher than those in the group (P＜0.01), and were higher than those in the control group ( P＜0.01).The WCST total responses, persistent errors, and random errors at the end of 12th week after intervention in the study group were lower than those in the group ( P ＜0.05 ); The number of correct responses and the number of completed classifications were higher than those in the group (P＜0.05).The number of WCST total response, persistent errors, and random errors were lower in the study group than those in the control group on the 12th week after intervention (P＜0.05).The number of correct responses and the number of completed classifications were higher than those in the control group (P＜0.05). Conclusion Non-drug treatment has obvious effects on improving the cognitive function of convalescent schizophrenia patients.