盐酸曲马多片缓解牙齿正畸后牙周疼痛的临床疗效观察

摘要

目的：探讨盐酸曲马多片缓解牙齿正畸后牙周疼痛的临床疗效。方法：将76名牙齿正畸患者随机分成I、II、III、IV 4组，用双盲法按不同剂量和不同方式给予盐酸曲马多片或安慰剂，在自然状态和牙齿咬合状态时，分别进行VAS问卷调查分析，同时登记药物不良反应情况。结果：各组牙齿咬合状态下较自然状态下疼痛明显；用药组疼痛均较对照组有所缓解，多次用药效果优于单次有药，各组均未出现明显不良反应。结论：盐酸曲马多片可缓解患者牙齿正畸后牙周疼痛不适。%Objective:To investigate the efficacy of tramadol hydrochloride tablets in the control of periodontal pain following ortho-dontic treatment.Methods:76 orthodontic patients were randomly assigned to I,II,III and IV groups according to the different doses of tramadol hydrochloride tablets or placebo(control).Periodontal pain was recorded and analysed by VAS,adverse reaction was ob-served.Results:The pain scores were all lower when teeth were not touching than when teeth were touching.Pain scores of experi-mental group were less than that of the control group,muff-doses are more effective than single-dose.No obvious adverse reaction was found in all group.Conclusion:Tramadol hydrochloride tablet is effective in the control of the pain following orthodontic treatment.