外阴恶性肿瘤79例临床治疗方法及预后分析

摘要

目的:探讨外阴恶性肿瘤不同治疗方法的临床效果及预后.方法:对2000年1月至2010年6月本院收治的79例外阴恶性肿瘤的治疗及预后进行回顾性研究.结果:Ⅰ、Ⅱ、Ⅲ、Ⅳ期的3年、5年生存率比较差异均有统计学意义(P＜0.05)；部分性外阴根治术组与传统全外阴根治术组3年、5年生存率比较差异无统计学意义(P＞0.05)；外阴癌根治术加放疗与单纯放疗5年生存率比较差异有高度统计学意义及统计学意义(P＜0.05)；腹股沟淋巴结阴性患者的5年生存率与阳性患者比较及盆腔淋巴结阴性患者的5年生存率与阳性患者比较差异有高度统计学意义及统计学意义(P＜0.01,P＜0.05).结论:临床分期及淋巴结转移状况是对外阴恶性肿瘤的预后具有显著影响的两个因素.外阴恶性肿瘤的治疗方式应具个体化.%Objective:To probe the clinical effects and prognosis of different methods in the treatment of patients with vulvar malignant tumor. Methods:The treatment and prognosis of 79 cases with vulvar malignant tumor in our hospital from Jan 2000 to June 2010 were retrospectively analyzed. Results .There was statistical difference between 3-year and 5-year survival rate about FIGO stage I , II , III and (V ( P < 0. 05). There was no statistical difference about survival between partly vulvectomy and conventional radical vulvectomy(P>0. 05). There was statistical difference about 5-year survival rate between radical vulvectomy plus postoperative radiation therapy( PORT)and radiation therapy( RT) (P<0. 05). There was statistical difference about 5-year survival rate between Inguinal lymph node and pelvic lymph node negative and positive (P<0.01, P<0.05). Conclusions:FIGO stages and lymph node metastasis are the two important prognostic factors of vulvar malignant tumor. The treatment of vulvar malignant tumor should be individualized.