目的:为探讨异时性多原发性结直肠癌的临床病理特点和诊治特点.方法:回顾分析13例异时性多原发性结直肠癌患者的病例资料,结合文献报道对异时性多原发性结直肠癌的发病状况,发病因素,诊断治疗及预后进行讨论.结果:异时性多发性结直肠癌病例占同期所有收治结直肠癌的1.36％(13/955),占多发性结直肠癌的34.21％(13/38),平均间隔时间为2.8年,均为肠镜随访发现,13例患者首发癌均行手术切除,再发癌以Dukes B期多见.结论:异时性多原发性结直肠癌临床病理学特点突出,应重视术后肠镜复查,早期发现,积极手术,提高患者生存率.%Objective To get a clearer understanding on the clinicopathological characteristics and the diagnosis and treatment of metachronous multiple primary colorectal carcinoma (MMPCC). Method The clinical data of 13 patients with MMPCC, received in our hospital in 2005-2011, were retrospectively analyzed. Results The percentage of patients with MMPCC was 1.36% (13/955) and the average interval was 2.8 years. All cases were diagnosed by colonoscopy. Surgical resection was performed on 13 patients. The recurrent carcinoma most often happened at Dukes B stage. Conclusion Metachronous colorectal carcinoma has special clinical and pathological features, and colonoscopy is critical to its diagnosis. Early detection, early diagnosis and early treatment can improve the prognosis.
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