宣肺通腑法在重症肺炎集束化治疗中的临床观察

摘要

Objective To observe the clinical efficacy of Xuanfeitongfu method in treatment of severe pneumonia and to explore its clinical value in the management of severe pneumonia. Methods Totally,62 patients with severe pneumonia were randomly divided into the control group (n = 30) and the treatment group (n = 32). The control group was given cluster treatment,including oxygen cure,anti-infection and nutrition support and maintaining a stable internal environment and etc. The treatment group was treated with Tongfu decoction orally(one dose a day,a total of 5 days)on a basis of cluster treatment. The comparison was conducted in the 2 groups in the levels of C reaction protein,calcitonin,the change of blood gas analysis,the time of mechanical ventilation and the mortality of severe pneumonia in ICU at baseline and 3,5 days after treatment. Results The level of C-reactive protein,calcitonin,the change of blood gas analysis were statistically significant (P < 0.05). The time of mechanical ventilation and the mortality were better in the treatment group (P < 0.05). Conclusion Xuanfeitongfu method can effectively improve oxygenation ,assist the anti-infection effect ,reduce the time of mechanical ventilation and ICU retention time ,ultimately improve the outcome of severe pneumonia.%目的:观察宣肺通腑法在重症肺炎集束化治疗中的临床疗效,探讨其在重症肺炎治疗中的临床价值.方法:将62例重症肺炎患者随机分为对照组(n=30)和治疗组(n=32).对照组给予氧疗、抗感染、营养支持及维持内环境稳定等集束化治疗;治疗组在集束化治疗基础上加用晁老通腑方汤剂口服,每天1剂,共5d.比较两组患者在治疗前及治疗后第3、5天血C-反应蛋白、降钙素原、血气分析的变化,机械通气时间及住ICU时间、因为重症肺炎导致的死亡率,并进行统计学分析.结果:两组患者在治疗后第3、5天血C-反应蛋白、降钙素原、血气分析等方面比较差异均有统计学意义(P<0.05);两组机械通气时间、住ICU时间及死亡率比较,治疗组预后更佳(P<0.05).结论:宣肺通腑法在重症肺炎集束化治疗中能有效改善氧合,协助抗炎、抗感染作用,减少机械通气时间及留住ICU时间,可以有效提高重症肺炎的治疗效果.