颈部单倍与双倍剂量增强磁共振血管造影对比研究

摘要

Objective To investigate the advantage of using double-dose contrast agent in contrast enhance-ment MRA (CE-MRA) on neck. Methods Totally 400 cases had undergone 3D-CE-MRA on neck. 200 cases were examed by single-dose (0.2 ml/kg) Gadodiamide, and 200 cases were examed by double-dose (0.4 ml/kg) Gadodi-amide. All acquired coronal pictures were reconstructed using MIP method and were observed by two experienced ra-diologist at the same time. The results were analyzed by two independent sampler non-parametric test in SPSS. Re-sults Among 200 cases using single-dose Gadodiamide, excellent pictures were 122 cases, good pictures were 50 cases, and non-satisfaction pictures were 28 cases. Among 200 cases using double-dose Gadodiamide, excellent pic-tures were 165 cases, good pictures were 30 cases, and non-satisfaction pictures were 5 cases. Conclusion Pictures of carotid artery using double-dose contrast agent are better than those using single-dose contrast agent. And thus may reduce error in clinical practice.%目的探讨使用双倍剂量对比剂在颈部对比增强磁共振血管造影（CE-MRA）检查中的优势。方法选取行颈部CE-MRA检查的患者400例，200例用单倍剂量对比剂，200例用双倍剂量对比剂，行3D-CE-MRA扫描，经最大密度投影法（MIP）重组获得整体血管图像，并结合原始图像进行分析。所得结果采用2个独立样本的非参数检验方法进行分析。结果200例使用单倍剂量对比剂的患者，图像质量优者为122例，良50例，差28例；200例双倍剂量患者，图像质量优者165例，良30例，差5例。结论采用双倍剂量对比剂所获得的颈部动脉血管图像优于单倍剂量对比剂所得的图像质量，有利于减少误差。