77例门脉高压性胃病临床分析

摘要

Objective To investigate the clinical features of portal hypertensive gastropathy (PHG). Method The retrospective analysis was conducted in 77 patients with PHG. The Child-Pugh scores of liver function,the severity of esophagus varices (EV),diameters of portal vein and splentic vein,and helicobacter pylori infection were evaluated. Results Out of 77 patients with PHG,the foci located in the fundic in 56 (72.7%); according to Tanoue classification,25 cases was grade 1,35 cases was grade II and 17 was grade III;The extent of PHG was related to Child-Pugh scores of liver function,the degree of EV and diameter of portal vein or splentic vein (P<0.05); However, HP infection was not different in different PHG patients(P> 0.05 ). Conclusion Child-Pugh scores, EV and diameter of portal vein or splentic vein are related to the extent of PHG.%目的 探讨门脉高压性胃病(PHG)的临床特征.方法 回顾性分析77例PHG患者的临床资料,分析Child-Pugh分级、食管胃底静脉曲张(EV)、门静脉和脾静脉直径及幽门螺杆菌(HP)感染对PHG的影响.结果 在77例PHG患者中,病变主要位于胃底者56例(72.7％)；按照Tanoue分类法Ⅰ级25例,Ⅱ级35例,Ⅲ级17例；PHG严重程度与Child-Pugh分级程度呈正相关(r=18.129,P＜0.05)；PHG严重程度与EV程度有统计学相关(r=22.121,P＜0.05)；PHG严重程度与门静脉和脾静脉直径均成正相关(r=13.101,P＜0.05；r=10.290,P＜0.05)；PHG严重程度与HP感染与否无显著相关性(r=0.668,P＞ 0.05).结论 PHG发生于患者肝功能、EV程度、门静脉和脾静脉直径有一定的相关性.