目的:分析北京市中学生不同腰围水平与代谢综合征相关性状的关系,为我国学龄儿童青少年腰围标准制定提供依据.方法:选择北京市1427名13～18岁中学生,测量身高、体重、腰围、血压、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和血糖.结合中国儿童青少年腰围正常值P75和P90,将对象分为3组.依据中国肥胖问题工作组体质指数(body mass index,BMI)超重肥胖筛查标准和2005年国际糖尿病联盟发布的代谢综合征标准,分析不同腰围组BMI超重肥胖情况,及其与代谢综合征相关性状关系.结果:高腰围水平组与低腰围水平组相比,代谢综合征各相关性状中高密度脂蛋白胆固醇均值降低,其余各指标均值均增加.除血糖和女生总胆固醇及甘油三酯外,各性状在不同腰围组差异均有统计学意义.高腰围水平组代谢综合征各组分除高血糖和女生高甘油三酯血症外发生率均显著增加,各组分聚集性也显著增加.不同腰围水平组与基于BMI的超重、肥胖筛查标准有较好相关性.结论:P75和P90的腰围分组能较好地指示代谢综合征各组分,提示心血管危险的增加.%Objective: To analyze the relationship between waist circumference ( WC ) and metabolic syndrome ( MS) related traits among middle school students in Beijing and to provide the proof for making WC cut-offs among Chinese children and adolescents. Methods; In the study, 1 427 students aged 13 -18 years were investigated. The indexes included height, weight, WC, blood pressure, total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and fasting blood glucose. The subjects were divided into three WC groups by using P75 and P90 of WC reference norms for Chinese children and adolescents. Obesity and MS components were assessed with the criteria of Working Group on Obesity in China and International Diabetes Federation, respectively. Results; HDL-cholesterol in high WC group was lower than that in low WC group. and other MS related traits showed the opposite direction. Excepting fasting glucose, female total cholesterol and triglycerides, MS related traits were different significantly within the WC groups. Excepting raised fasting blood glucose and female raised triglycerides, the prevalence of MS components increased and aggregated in high WC group significantly. The distribution of different WC groups was correlated with that of obesity groups based on body mass index criterion. Conclusion: The P75 and P90 of WC reference norms could well indicate the increase of the prevalence of MS components, suggesting the increased risk for cardiovascular disease.
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